B7-H1 Antigen

An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.

Also Known As:

B7-H1 Immune Costimulatory Protein; B7H1 Immune Costimulatory Protein; CD274 Antigen; PD-L1 Costimulatory Protein; Programmed Cell Death 1 Ligand 1; Antigen, B7-H1; Antigen, CD274; B7 H1 Antigen; B7 H1 Immune Costimulatory Protein; CD274 Antigens; Costimulatory Protein, PD-L1; PD L1 Costimulatory Protein; PD L1 Protein; Antigens, CD274; PD-L1 Protein; Programmed Cell Death 1 Ligand 1 Protein; Programmed Death Ligand 1

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - B7 Antigens: 156
      - B7-H1 Antigen: 4390
  - Membrane Proteins: 10262
    - B7 Antigens: 156
      - B7-H1 Antigen: 4390
  - Immune Checkpoint Proteins: 1318
    - B7-H1 Antigen: 4390
Biological Factors: 2560
- Antigens: 145631
  - Surface Antigens: 5857
    - B7 Antigens: 156
      - B7-H1 Antigen: 4390
- Intercellular Signaling Peptides and Proteins: 30151
  - B7 Antigens: 156
    - B7-H1 Antigen: 4390

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